Here
are detailed explanations of the rating levels used on BioValidity's site
for human knowledgebases.
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Strong Statements -
Supported by STRONG scientific evidence, demonstrated by clinical
findings in humans.
- Evidence of at least one randomized, prospective, double-blind,
placebo-controlled clinical trial in humans using
adequate statistical power that demonstrates a significant effect or
improvement on a health-related endpoint.
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- Research findings are consistent and widely accepted.
- Results are published in well-respected, peer-reviewed
journals.
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Substantial Statements -
Supported by SUBSTANTIAL scientific evidence found in human or
animal studies.
- Research finds may be mixed; however, based on the judgement
of the reviewers, there is adequate agreement.
- Where ethically possible, there are at least two clinical
experimental or quasi-experimental human studies (eg,
single-blinded, un-blinded, non-randomized, non-placebo
controlled) that show a significant effect or improvement on a
health-related endpoint.
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- Multiple animal studies on a basic process that are considered
to be applicable to humans.
- Biochemical studies that are consistent with human and animal
experiments and other scientific findings.
- Results are published in well-respected, peer-reviewed
journals.
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Limited Statements -
Supported by LIMITED clinical or scientific evidence that is
suggestive, but not definitive.
- If possible, at least one human study that shows a significant
effect (but not meeting strong or substantial criteria) or several
animal studies that substantially agree on the presence of a
significant effect (demonstrating a high potential).
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- Animal studies on a basic process that are considered to be
applicable to humans.
- Some in vitro or biochemical studies that are consistent with
human or animal experiments and other scientific findings.
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- Results are published in mainstream scientific journals or
well-respected alternative medical/scientific journals.
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Minimal Statements -
Supported by MINIMAL scientific evidence.
- Results may be found in mainstream scientific journals, but are at a very preliminary stage and do not demonstrate a health-related value.
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No Scientific Evidence -
Supported by NO scientific evidence, instead supported by
anecdotal or historical evidence unproven by conventional research
standards.
- Asserted by alternative health practitioners and published in
alternative nutritional or trade media.
- Research findings are unproved by conventional research
standards.
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